Dextramer® BV421 is Here!

Extra Flexibility for Your Antigen-Specific Immune Cell Monitoring 

  • MHC Dextramer®, Klickmer® and U-Load® reagents are now available as standard products with BV421 fluorochrome 

  • Greater flexibility for the detection of antigen-specific T and B cells by flow cytometry 

  • Facilitates inclusion of Dextramer®-based multimers in antibody panels  

  • You can request other products with the BV421 fluorochrome, e.g. DNA barcoded dCODE® Dextramer, Klickmer and U-Load reagents for single-cell analysis via Custom Solutions and Services 

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Prices of reagents with the BV421 fluorochrome are visible in our webshop. Alternatively, please contact us to request a quotation for your reagents of interest with the BV421 fluorochrome.

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Add a touch of brilliance to your immune cell monitoring with the BV421 fluorochrome. The addition of BV421 makes it easier to combine Dextramer®-based multimers with antibody panels for characterization of immune cells by flow cytometry.  

The BV421 fluorochrome is available as standard for all MHC Dextramer® reagents for detection of CD4+ and CD8+ T cells, MAIT cells, and NKT cells. In addition, Klickmer® (for the detection of B cells and more) and U-Load® reagents are available with BV421. 

 

Please note that BD Horizon™ Brilliant Stain Buffer is required when using reagents labeled with BV421, as described in the MHC Dextramer® Staining Protocol here, and must be purchased separately from BD.

Add BV421 to your Immune Monitoring

Multicolor Phenotyping using Immune Profiling Panels

See how MHC Dextramer® BV421 reagents can easily be integrated as components in commercial immune cell profiling panels to extend the analysis of surface markers to include information about antigen specificity. ​

Read more

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What's your Favorite Fluorochrome?

Is there a particular fluorochrome that you would love to add to your Dextramer® reagents?  

Let us know by taking part in the favorite fluorochrome survey! 

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BV421 is equivalent to Brilliant Violet™ 421, which is a trademark or registered trademark of Becton, Dickinson and Company or its affiliates, and is used under license. Powered by BD Innovation.