T-Cell Monitoring with the Power of Multiplexing

dCODE Dextramer® technology enables the analysis of antigen-specific T cells by NGS or single-cell multi-omics

dCODE Dextramer® adds a unique DNA barcode to the MHC Dextramer® reagent to detect antigen-specific T cells by NGS or single-cell multi-omics

  • High-avidity binding to T-cell receptors thanks to multiple MHC-peptide complexes
  • High-throughput screening with a unique barcode for each MHC-peptide specificity
  • Enrichment of low-frequency cells thanks to PE fluorochromes
  • Compatible with single-cell gene expression analysis

 

READ MORE DETAILS IN OUR FAQs

dCODE Dextramer®: Adapted to Fit Your Chosen Platform

All the different dCODE Dextramer® reagents available can be made to fit your working platform, for NGS, or single-cell multi-omics

dCODE Dextramer® (HiT)

For bulk analysis of antigen-specific T cells by NGS

dCODE Dextramer® (RiO)

For single-cell multi-omic analysis of antigen-specific T cells using the BD Rhapsody™ Single-Cell Analysis System

dCODE Dextramer® (10x)

For single-cell multi-omic analysis of antigen-specific T cells using the 10x Chromium Single Cell Gene Expression System

dCODE® Data Analysis Services

We have partnered with Ardigen, a world-leading AI CRO to provide Immune Profiling Multi-Omics Data Analysis Services. Using advanced platforms and expertise, Ardigen transforms multi-omics datasets generated using dCODE® reagents into ready-to-use scientific insights.

Learn more

dCODE Dextramer®: Adapted to Detect the Target of Your Interest

Whether it is T-cells, NKT cells, or beyond T cells, there is a dCODE Dextramer® that suits your needs to explore further in NGS or single-cell multi-omics

dCODE Dextramer®

Ready-to-use reagents for analysis of antigen-specific T cells

dCODE Klickmer®

Customizable analysis of any immune cells


U-Load dCODE Dextramer®

Produced in your own lab with the MHC complex and peptide specificity of your choice for analysis of T cells

MR1 dCODE Dextramer®​

Ready-to-use reagents for analysis of antigen-specific MAIT cells​

CD1d dCODE Dextramer®

Ready-to-use reagents for analysis of NKT cells

HLA-E and HLA-G dCODE Dextramer®

Ready-to-use reagents for analysis of antigen-specific NK or T cells

dCODE® BV421, FITC or APC

dCODE® reagents with BV421, FITC or APC fluorochromes available via Custom Solutions and Services

dCODE Dextramer® Applications

Explore selection of posters, case studies, and application notes.

 

Immudex is the sole manufacturer of dCODE Dextramer® reagents, and support related to these products is through Immudex.

The dCODE® technology is disclosed in granted and pending patents within the WO 2015/185067 and WO 2015/188839 patent families including US11402373, US11585806, US11668705, EP3152232, EP3155426, HK1236546 B, AU2015271324, AU2019264685, AU2021204496, CA2951325, SG11201610177U, JP6956632 and JP7271465.

BV421 is equivalent to Brilliant Violet™ 421, which is a trademark or registered trademark of Becton, Dickinson and Company or its affiliates, and is used under license. Powered by BD Innovation.